Alex Coles and Fraser Dingwall have been picked by Steve Borthwick to start for England this Sunday (23 November, kick-off: 4.10pm) at Allianz Stadium against Argentina, with Alex Mitchell and Henry Pollock set to come off the bench.
All four Saints men have featured in every matchday squad for England this autumn, with Dingwall being the only one to start every game.
“Last weekend gave us plenty to build on, and now the challenge is to push our performance further,” said head coach Borthwick.
“Argentina play with emotion and physicality, and they’ve shown they can beat the best in world rugby this year. We know how dangerous they can be, and we are preparing for a fiercely contested Test match.
“We have felt exceptional support at Allianz Stadium throughout this series. It provides a real lift for the players, and we hope to create lasting memories for our supporters on Sunday.”
England vs Argentina
Sunday 23 November
Kick-off: 4.10pm
Allianz Stadium, Twickenham
15. Freddie Steward (Leicester Tigers, 40 caps)
14. Immanuel Feyi-Waboso (Exeter Chiefs, 12 caps)
13. Henry Slade (Exeter Chiefs, 73 caps)
12. Fraser Dingwall (Northampton Saints, 7 caps)
11. Elliot Daly (Saracens, 73 caps)
10. George Ford (Sale Sharks, 104 caps) – vice-captain
9. Ben Spencer (Bath Rugby, 13 caps)
1. Ellis Genge (Bristol Bears, 74 caps) – vice-captain
2. Luke Cowan-Dickie (Sale Sharks, 52 caps)
3. Asher Opoku-Fordjour (Sale Sharks, 5 caps)
4. Maro Itoje (Saracens, 96 caps) – captain
5. Alex Coles (Northampton Saints, 13 caps)
6. Guy Pepper (Bath Rugby, 6 caps)
7. Sam Underhill (Bath Rugby, 44 caps)
8. Ben Earl (Saracens, 45 caps)
Replacements:
16. Theo Dan (Saracens, 19 caps)
17. Fin Baxter (Harlequins, 17 caps)
18. Will Stuart (Bath Rugby, 52 caps)
19. Charlie Ewels (Bath Rugby, 33 caps)
20. Tom Curry (Sale Sharks, 64 caps)
21. Henry Pollock (Northampton Saints, 4 caps)
22. Alex Mitchell (Northampton Saints, 26 caps)
23. Marcus Smith (Harlequins, 46 caps)