Day, who only toured with England Under-18 to Australia last summer, has been chosen by head coach Rob Hunter on the replacements' bench.
The former student of St Joseph's College in Ipswich is one of eight players who represented England Under-18 last season and Hunter is excited to see what his players have to offer.
He said: "We're excited about getting into the Six Nations, it's a new side and we are all looking forward to seeing them play. We have a good blend of experience and fresh faces.
"Competition for places is high and we are pleased with how the team has come together. There are no easy games in this tournament and starting off against Scotland in Glasgow will be tough."
Friday night's game will be streamed live on www.rfu.com
ENGLAND UNDER-20 TEAM TO PLAY SCOTLAND
Friday, February 3rd, 2012
Kick off 7:30pm
15 Ben Ransom (Saracens)
14 Marland Yarde (London Irish)
13 Elliot Daly (London Wasps)
12 Ryan Mills (Gloucester)
11 Charlie Walker (Harlequins)
10 George Ford (Leicester Tigers)(capt)
9 Dan Robson (Gloucester)
1 Luke Cowan-Dickie (Exeter Chiefs)
2 Koree Britton (Gloucester)
3 Kyle Sinckler (Harlequins)
4 Tom Price (Leicester Tigers)
5 George Merrick (Harlequins)
6 Matt Kvesic (Worcester Warriors)
7 Chris Walker (Leeds Carnegie)
8 Jack Clifford (Harlequins)
16 Scott Spurling (Saracens)
17 Alec Hepburn (London Wasps)
18 Ross Harrison (Sale Sharks)
19 Elliot Stooke (Gloucester)
20 Will Skuse (Bath)
21 Alex Day (Northampton Saints)
22 Tom Heathcote (Bath)
23 Anthony Watson (London Irish)