While it will be led once again by Sam Olver and includes the majority of the players that finished second in Group C last weekend, coach Mark Hopley has had to contend with the enforced absences of Harry Mallinder, James Fish and Lewis Ludlam, who are all touring with England Under-18 in South Africa.
Youngsters George Cox and Will Allman both come into the group that will travel to the Twickenham Stoop, as does Matt Goode, who has experience from the national Sevens circuit.
All eight qualifiers will open their respective evenings with a straight knockout quarter final, with the winners progressing into the Cup and the losers into the Plate.
Saints play Gloucester at 6:25pm, and you can watch the action live on BT Sport. Tickets for Friday night remain available via www.stubhub.co.uk
NORTHAMPTON SAINTS SEVENS SQUAD
Premiership Rugby Sevens Series Finals
Twickenham Stoop
Friday, August 8th, 2014
1 Josh SKELCEY
2 George COX
3 Glenn DICKSON
4 Tim CARDALL
5 Jacob CONNER
7 Will ALLMAN
8 Teimana HARRISON
9 Phil ROBINSON
10 Sam OLVER (capt)
11 Howard PACKMAN
12 Matt GOODE