Tom Wood is back to captain the team from the blindside, while Ben Nutley also comes in as the pack is shuffled - Calum Clark moving up to the second row and Phil Dowson wearing number 8.
Alex Corbisiero makes his first start since September on the loose head with the final change coming in the backs, where Jamie Elliott is on the right wing.
There is no television coverage from the AJ Bell Stadium tomorrow afternoon, but you can still follow the action as it happens at www.saintslive.co.uk. Score updates will also be available on the @SaintsRugby Twitter feed.
NORTHAMPTON SAINTS SIDE TO PLAY SALE
Aviva Premiership Rugby R13
AJ Bell Stadium
Saturday, January 10th, 2015
Kick off 2:00pm
15 Ben FODEN
14 Jamie ELLIOTT
13 George PISI
12 Luther BURRELL
11 George NORTH
10 Stephen MYLER
9 Lee DICKSON
1 Alex CORBISIERO
3 Salesi MA’AFU
4 Sam DICKINSON
5 Calum CLARK
6 Tom WOOD (capt)
7 Ben NUTLEY
8 Phil DOWSON
Replacements
16 Matti WILLIAMS
17 Alex WALLER
18 Gareth DENMAN
19 Jordan ONOJAIFE
20 Teimana HARRISON
21 Joel HODGSON
22 James WILSON
23 Ken PISI